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FineTest

SKU(재고 관리 코드):FNab00399

anti- ANGPTL4 antibody

anti- ANGPTL4 antibody

size

Uncover the intricate web of angiogenesis and vascular remodeling with our specialized Anti-ANGPTL4 Antibody, now available in a 100µg size. ANGPTL4, also known as fasting-induced adipose factor (FIAF), plays a pivotal role in regulating angiogenesis and lipid metabolism, making it a crucial focus for researchers exploring vascular biology and metabolic disorders.

Our Anti-ANGPTL4 Antibody is carefully designed to provide outstanding specificity and sensitivity, making it a versatile tool for various research applications, from immunohistochemistry to protein-protein interaction studies. Rigorous validation ensures consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With 100µg of high-quality antibody, this product offers sufficient material for multiple experiments, maintaining cost-effectiveness while ensuring research reliability. Its user-friendly design caters to researchers of all experience levels, enhancing the accuracy and dependability of experiments across diverse laboratory techniques.

Contribute to groundbreaking research in angiogenesis, vascular biology, and metabolic regulation with confidence, supported by our high-quality Anti-ANGPTL4 Antibody. Be part of advancements in understanding the complex mechanisms governing vascular development and their potential implications in metabolic health.

Product Name

ANGPTL4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity).

IMMUNOGEN INFORMATION

Immunogen

angiopoietin-like 4

Synonyms

Angiopoietin like 4, Angiopoietin like protein 4, Angiopoietin related protein 4, ANGPTL2, ANGPTL4, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, PSEC0166, UNQ171/PRO197

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, IHC, IF, IP, WB

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200; IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q9BY76

IMAGES

 

Immunohistochemistry of paraffin-embedded human kidney slide using FNab00399(ANGPTL4 Antibody) at dilution of 1:50
Immunofluorescent analysis of ( -20°C Ethanol) fixed HEK-293 cells using FNab00399 (ANGPTL4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
IP Result of anti-ANGPTL4 (IP:FNab00399, 4ug; Detection:FNab00399 1:500) with mouse heart tissue lysate 4000ug.
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00399(ANGPTL4 Antibody) at dilution of 1:1000

 

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