anti- APOBEC3C antibody

Uncover the intricacies of APOBEC3C with our Anti-APOBEC3C Antibody, now available in a convenient 100µg size. APOBEC3C, a member of the APOBEC3 family of proteins, is a key player in the innate immune response against viral infections.

This antibody is expertly designed for exceptional specificity and sensitivity, ensuring reliable and reproducible results in various applications, including Western blotting and immunohistochemistry. Whether you're exploring APOBEC3C's antiviral functions or its involvement in cancer biology, our antibody is your dependable research partner.

The 100µg size offers cost-effective flexibility, catering to both small-scale experiments and more extensive research projects. Its consistent quality and purity make it an ideal choice for researchers across disciplines, from virology to cell biology.

Choose our Anti-APOBEC3C Antibody to propel your research forward and gain deeper insights into APOBEC3C-related processes. Count on its performance and join the ranks of scientists who rely on our products to advance scientific understanding.

Product Name

APOBEC3C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

DNA deaminase(cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and-independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus(SIV), hepatitis B virus(HBV), herpes simplex virus 1(HHV-1) and Epstein-Barr virus(EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

IMMUNOGEN INFORMATION

Immunogen

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C

Synonyms

APOBEC1L, PBI

Observed MW

23 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9NRW3

IMAGES