anti- ASK1 antibody

Embark on a journey to explore signaling pathways with our Anti-ASK1 Antibody, available in a convenient 100µg size. ASK1, a critical kinase in the MAP kinase signaling cascade, is involved in cell growth, apoptosis, and stress responses.

Our meticulously developed monoclonal antibody ensures unparalleled specificity and sensitivity. Whether you're conducting Western blotting, immunoprecipitation, or immunofluorescence, trust in our antibody to deliver consistent and reliable results.

The 100µg size provides an ample supply for your experiments, minimizing interruptions and allowing you to maintain the momentum of your research.

Don't miss the opportunity to shed light on the multifaceted functions of ASK1 and its role in cellular signaling. With our Anti-ASK1 Antibody, you can confidently delve into your research and uncover the secrets hidden within this pivotal kinase.

Product Name

ASK1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species(ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase(JNK) and p38.

IMMUNOGEN INFORMATION

Immunogen

mitogen-activated protein kinase kinase kinase 5

Synonyms

ASK 1, ASK1, MAP3K5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5

Observed MW

155 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:100-1:1000

UNIPROT INFORMATION

UniProt ID

Q99683

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