anti- ATF2 antibody

Navigate the world of transcriptional regulation with our Anti-ATF2 Antibody, now available in a 100µg size. ATF2, a pivotal transcription factor, is involved in a wide range of cellular processes, including stress responses, DNA repair, and cell cycle control.

Our meticulously developed monoclonal antibody ensures unparalleled specificity and sensitivity, making it the ideal choice for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The 100µg size provides an ample supply for your experiments, minimizing interruptions and allowing you to maintain the momentum of your research.

Don't miss the opportunity to shed light on the multifaceted functions of ATF2 in transcriptional regulation. With our Anti-ATF2 Antibody, you can confidently delve into your research and uncover the secrets hidden within this essential transcription factor.

Product Name

ATF2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene

IMMUNOGEN INFORMATION

Immunogen

activating transcription factor 2

Synonyms

CREB2, CREBP1

Observed MW

70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P15336

IMAGES