anti- BCOR antibody

Decipher the functions of BCOR in epigenetic regulation with our Anti-BCOR Antibody. This 100µg antibody is your passport to exploring the roles of BCOR, a critical protein involved in chromatin modification and gene expression control.

Engineered for precision and reliability, this antibody excels in various applications, from chromatin immunoprecipitation to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, making it an invaluable tool in your research.

BCOR, also known as BCL-6 corepressor, is central to epigenetic regulation and has implications in cancer research and developmental biology. With this antibody in your arsenal, you're better equipped to investigate its functions. Whether you're studying chromatin remodeling or its role in gene silencing, this antibody is your trusted research companion.

Illuminate the path to scientific discovery by ordering your Anti-BCOR Antibody today and gain deeper insights into the dynamic world of BCOR biology.

Product Name

BCOR antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2).

IMMUNOGEN INFORMATION

Immunogen

BCL6 co-repressor

Synonyms

KIAA1575

Observed MW

186 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

Q6W2J9

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