anti- BPGM antibody

Uncover the functionality of BPGM (Bisphosphoglycerate Mutase) with our Anti-BPGM Antibody, available in a 100µg size. This antibody is your indispensable tool for investigating the roles and mechanisms of BPGM in glycolytic regulation and cellular metabolism.

Engineered for precision and reliability, this antibody offers exceptional specificity and sensitivity, ensuring accurate results in applications such as western blotting, immunofluorescence, and enzyme assays. Whether you're probing BPGM's involvement in energy metabolism, oxygen transport, or disease pathogenesis, this antibody enhances your research capabilities.

BPGM, a key enzyme in the glycolytic pathway, catalyzes the conversion of 1,3-bisphosphoglycerate to 2,3-bisphosphoglycerate, thereby regulating oxygen affinity of hemoglobin and oxygen transport in erythrocytes.

With our Anti-BPGM Antibody, you can uncover BPGM's functionality, investigate its regulatory mechanisms, and potentially advance research in biochemistry and hematology. Elevate your research in cellular metabolism and enzyme kinetics with this precision antibody.

Product Name

BPGM antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

2, 3-diphosphoglycerate (2, 3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2, 3-DPG synthesis via its synthetase activity, and 2, 3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

IMMUNOGEN INFORMATION

Immunogen

2, 3-bisphosphoglycerate mutase

Synonyms

DPGM

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P07738

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