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SKU(재고 관리 코드):FNab00975

anti- BTD antibody

anti- BTD antibody

size

Study BTD (Biotinidase) with our Anti-BTD Antibody, available in a 100µg size. This high-quality antibody is your versatile tool for investigating BTD's roles in biotin metabolism, enzymatic activity, and genetic disorders.

Engineered for precision and reliability, this antibody ensures exceptional sensitivity in applications such as western blotting, immunohistochemistry, and enzymatic assays. Whether you're exploring BTD's involvement in biotin recycling, carboxylase activation, or its interactions with biotinidase-deficiency-associated mutations, this antibody enhances your research capabilities.

BTD, a biotin-recycling enzyme, plays a crucial role in maintaining biotin homeostasis and preventing biotin deficiency. Understanding BTD's functions and its genetic variations is fundamental in deciphering its contributions to metabolic processes and biotin-responsive disorders.

With our Anti-BTD Antibody, you can delve into BTD's functionality, explore its enzymatic activity, and potentially advance research in biotin metabolism and the treatment of biotinidase deficiency. Elevate your research in metabolic disorders and enzymatic pathways with this precision antibody.

Product Name

BTD antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene functions to recycle protein-bound biotin by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. The encoded protein has also been shown to have biotinyl transferase activity. Mutations in this gene are associated with biotinidase deficiency. Multiple transcript variants encoding different isoforms have been described.

IMMUNOGEN INFORMATION

Immunogen

biotinidase

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

P43251

IMAGES

 

Immunohistochemistry of paraffin-embedded human liver cancer using FNab00975(BTD antibody) at dilution of 1:100
HeLa cells were subjected to SDS PAGE followed by western blot with FNab00975(BTD antibody) at dilution of 1:1000

 

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