anti- BVES antibody

Investigate the multifaceted functions of BVES (Blood Vessel Epicardial Substance) with our Anti-BVES Antibody, available in a 100µg size. This high-quality antibody is your versatile tool for studying BVES's roles in cell adhesion, cardiovascular development, and epithelial biology.

Engineered for precision and reliability, this antibody ensures exceptional sensitivity in applications such as western blotting, immunohistochemistry, and immunofluorescence. Whether you're exploring BVES's role in cell junction formation, tissue morphogenesis, or its interactions with other adhesion molecules, this antibody enhances your research capabilities.

BVES, a transmembrane protein, plays a critical role in regulating epithelial cell adhesion and cardiovascular development. Its involvement in tissue remodeling and cell-cell interactions makes it a key player in various physiological processes.

With our Anti-BVES Antibody, you can delve into BVES's functionality, explore its impact on cell adhesion, and potentially advance research in cardiovascular biology and tissue morphogenesis. Elevate your research in epithelial biology and cardiovascular development with this precision antibody.

Product Name

BVES antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction(TJ) paracellular permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.

IMMUNOGEN INFORMATION

Immunogen

blood vessel epicardial substance

Synonyms

BVES, HBVES, POP1, POPDC1, Popeye protein 1

Observed MW

41-70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:100-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8NE79

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