anti- CBX5 antibody

Embark on a journey into the fascinating world of chromatin structure and gene regulation with our Anti-CBX5 Antibody, available in a 100µg size. CBX5, also known as Chromobox Protein Homolog 5 or HP1 Alpha, is a key component of heterochromatin, playing a critical role in gene silencing and chromatin compaction. This antibody is meticulously developed to offer exceptional specificity and sensitivity, making it an invaluable tool for your research endeavors.

CBX5's involvement in epigenetic regulation and heterochromatin formation has implications for diverse biological processes, including transcriptional repression and genome stability. Whether you're conducting chromatin immunoprecipitation (ChIP), immunofluorescence, or studying chromatin structure, this antibody provides reliable and consistent results, ensuring the success of your research.

With 100µg of antibody in each vial, you'll have an ample supply to support multiple experiments, promoting cost-effectiveness without compromising data quality. Dive into the world of chromatin biology and epigenetics research with confidence using our Anti-CBX5 Antibody.

Product Name

CBX5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

IMMUNOGEN INFORMATION

Immunogen

chromobox homolog 5 (HP1 alpha homolog, Drosophila)

Synonyms

HP1A

Observed MW

23 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P45973

IMAGES