anti- CDCA5 antibody

Embark on a journey into the world of chromosome dynamics and cell division with our Anti-CDCA5 Antibody, available in a 100µg size. CDCA5, or cell division cycle-associated 5, is a key component of the chromosomal passenger complex (CPC), essential for proper chromosome segregation during mitosis.

This monoclonal antibody offers high specificity and sensitivity, making it a valuable tool for researchers investigating cell cycle regulation, mitosis, and the molecular mechanisms governing chromosome behavior. With 100µg of this antibody, you'll have an ample supply for multiple experiments, ensuring the continuity of your research.

Uncover the intricate role of CDCA5 in chromosome dynamics during cell division. Investigate its interactions with other CPC components and its potential implications in cancer biology, genomic stability, and therapeutic interventions.

Product Name

CDCA5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.

IMMUNOGEN INFORMATION

Immunogen

cell division cycle associated 5

Observed MW

37kd

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q96FF9

IMAGES

A549 cells were subjected to SDS PAGE followed by western blot with FNab01542(CDCA5 antibody) at dilution of 1:500