anti- CDH23 antibody

Delve into the fascinating world of sensory function and hearing with our Anti-CDH23 Antibody, available in a 100µg size. Cadherin-23 (CDH23) is a transmembrane protein crucial for the development and maintenance of sensory hair cells in the inner ear, making it a key target for research in auditory biology and sensory perception.

Our meticulously developed monoclonal antibody offers exceptional sensitivity and specificity, making it an indispensable tool for researchers investigating sensory hair cell development, hearing loss, and the molecular mechanisms governing auditory function. With 100µg of this antibody, you'll have an ample supply for multiple experiments, ensuring the continuity of your research.

Uncover the intricacies of CDH23 and its significance in sensory function, hair cell mechanotransduction, and auditory disorders. Investigate its interactions with other proteins involved in auditory signal transduction and its potential implications in hearing-related research, regenerative medicine, and therapeutic interventions.

Product Name

CDH23 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

IMMUNOGEN INFORMATION

Immunogen

cadherin-like 23

Synonyms

KIAA1774, KIAA1812

Observed MW

59 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9H251

IMAGES