anti- CENPH antibody

Embark on a journey into the realm of centromere dynamics and chromosome segregation with our Anti-CENPH Antibody, now available in a 100µg size. CENPH, or centromere protein H, is a critical player in centromere function, ensuring the faithful transmission of genetic material during cell division. This monoclonal antibody offers remarkable specificity and sensitivity, making it an indispensable tool for researchers exploring cell cycle regulation, mitosis, and the molecular mechanisms governing centromere maintenance.

With 100µg of this antibody, you'll have an ample supply for various experiments, ensuring the continuity of your research. Decipher the complexities of CENPH and its role in centromere stability, its interactions with kinetochore components, and its potential implications in cancer biology, chromosome segregation disorders, and therapeutic interventions.

Product Name

CENPH antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the CENPA-NAC(nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD(nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.

IMMUNOGEN INFORMATION

Immunogen

centromere protein H

Synonyms

ICEN35

Observed MW

28-38 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9H3R5

IMAGES

Hela cells were subjected to SDS PAGE followed by western blot with FNab01586(CENPH antibody) at dilution of 1:5000