anti- CHMP2B antibody

Step into the world of endosomal trafficking and vesicle formation with our Anti-CHMP2B Antibody, available in a 100µg size. Charged multivesicular body protein 2B (CHMP2B) is a key player in the ESCRT-III complex, crucial for membrane remodeling and cargo sorting.

This high-quality polyclonal antibody is meticulously designed to provide exceptional specificity and sensitivity, ensuring accurate detection of CHMP2B protein in your experiments. Researchers investigating endosomal maturation, autophagy, or related fields will appreciate the precision and reliability of this antibody.

Our Anti-CHMP2B Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Join the forefront of membrane biology research and gain valuable insights into the mechanisms governing intracellular vesicle formation.

Product Name

CHMP2B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

IMMUNOGEN INFORMATION

Immunogen

chromatin modifying protein 2B

Observed MW

28 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9UQN3

IMAGES