anti- CHTF18 antibody

Delve into the world of DNA replication and genome stability with our Anti-CHTF18 Antibody, available in a 100µg size. Chromosome Transmission Fidelity 18 (CHTF18) is a key protein involved in the regulation of DNA replication and the maintenance of chromosomal integrity.

This meticulously designed antibody offers unparalleled specificity and sensitivity, ensuring accurate detection of CHTF18 protein in your experiments. Researchers investigating DNA replication, cell cycle progression, or related areas will benefit from the precision and reliability of this antibody.

Our Anti-CHTF18 Antibody undergoes stringent quality control, guaranteeing consistent and reproducible results. Take your research on genome stability and DNA replication to the next level with this essential tool.

Product Name

CHTF18 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C(CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A(RPA) and by proliferating cell nuclear antigen(PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.

IMMUNOGEN INFORMATION

Immunogen

CTF18, chromosome transmission fidelity factor 18 homolog

Synonyms

C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, CHTF18, Ctf18, hCTF18, RUVBL

Observed MW

120kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8WVB6

IMAGES

Immunohistochemistry of paraffin-embedded human cerebellum using FNab01701(CHTF18 antibody) at dilution of 1:100

Y79 cells were subjected to SDS PAGE followed by western blot with FNab01701(CHTF18 antibody) at dilution of 1:300