anti- CNTN1 antibody

Dive into the world of neural cell adhesion with our Anti-CNTN1 Antibody, available in a convenient 100µg size. Contactin 1 (CNTN1) is a crucial molecule involved in the formation and maintenance of neural circuits, making this antibody an invaluable tool for your research.

Our meticulously crafted antibody has undergone rigorous quality control measures to ensure specificity and sensitivity, ensuring accurate and reproducible results in your experiments. Whether you're investigating axon guidance, neuronal connectivity, or neurodevelopmental disorders, this antibody will be your trusted companion.

The 100µg size provides a generous supply of antibody to support your experiments without the hassle of frequent reordering. Trust in our Anti-CNTN1 Antibody to accelerate your scientific exploration of neural cell adhesion and contribute to the understanding of neural circuitry.

Product Name

CNTN1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain(NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth(By similarity).

IMMUNOGEN INFORMATION

Immunogen

contactin 1

Observed MW

135 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q12860

IMAGES

rat brain tissue were subjected to SDS PAGE followed by western blot with FNab01821( CNTN1 Antibody) at dilution of 1:1200