anti- COTL1 antibody

Enter the realm of immune regulation and T-cell biology with our Anti-COTL1 Antibody, meticulously crafted and available in a convenient 100µg size. COTL1, also known as CARMA1, is a critical component of the CARMA1-BCL10-MALT1 (CBM) complex, playing a pivotal role in T-cell receptor signaling and immune response activation. This high-quality antibody serves as your essential tool for investigating the intricate processes of immune cell activation and signaling cascades.

Our antibody is thoughtfully designed and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your research. Whether you're exploring autoimmune diseases, T-cell signaling, or the role of COTL1 in lymphocyte activation, this antibody is your dependable research companion.

The 100µg size offers a substantial supply of antibody for your experiments, reducing the inconvenience of frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-COTL1 Antibody to advance your scientific exploration of immune regulation and contribute to a deeper understanding of T-cell biology.

Unraveling the intricacies of COTL1's role in immune signaling and its impact on autoimmune disorders is essential for deciphering the complexities of immune-mediated diseases and their implications for therapeutic interventions. Our antibody empowers you to delve into this intriguing area of research, potentially paving the way for novel immunomodulatory strategies and improved patient care.

Product Name

COTL1 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5(5LO), influencing both its stability and activity in leukotrienes synthesis.

IMMUNOGEN INFORMATION

Immunogen

coactosin-like 1

Synonyms

CLP, Coactosin like protein, COTL1

Observed MW

16 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:1000-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q14019

IMAGES