anti- COX6B1 antibody

Delve into the intricate world of mitochondrial biology with our Anti-COX6B1 Antibody, available in a convenient 100µg size. Cytochrome c oxidase subunit 6B1 (COX6B1) is a crucial player in the electron transport chain, contributing to the efficient conversion of oxygen and electrons into cellular energy.

This antibody is rigorously validated for specificity and sensitivity, making it suitable for various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. Whether you are researching mitochondrial diseases, cellular respiration, or oxidative stress, our Anti-COX6B1 Antibody will provide you with accurate and consistent results.

Count on this antibody to empower your investigations into mitochondrial function, energy metabolism, and related fields, as you uncover the molecular mechanisms driving ATP production and cellular bioenergetics.

Product Name

COX6B1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

IMMUNOGEN INFORMATION

Immunogen

cytochrome c oxidase subunit Vib polypeptide 1 (ubiquitous)

Synonyms

COX6B

Observed MW

13 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P14854

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