anti- CRK antibody

Explore the world of cellular signaling and adaptor proteins with our Anti-CRK Antibody, available in a convenient 100µg size. CRK is a versatile adaptor protein involved in mediating protein-protein interactions and signaling events crucial for cell proliferation, migration, and differentiation.

This antibody is meticulously designed and rigorously tested for specificity and sensitivity, making it suitable for various applications, including Western blotting, immunoprecipitation, and immunocytochemistry. Whether you are studying cancer biology, cell signaling pathways, or cytoskeletal dynamics, our Anti-CRK Antibody will provide you with precise and reliable results.

Count on the accuracy and reliability of this antibody as you advance your research in molecular biology, cell physiology, and related fields. Uncover the molecular mechanisms governing CRK's roles in coordinating intracellular signaling events and cellular responses with the assistance of this high-quality antibody.

Product Name

CRK antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

IMMUNOGEN INFORMATION

Immunogen

v-crk sarcoma virus CT10 oncogene homolog (avian)

Observed MW

37 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P46108

IMAGES