anti- CSNK1A1 antibody

Enter the dynamic world of protein kinase CSNK1A1 with our Anti-CSNK1A1 Antibody, now available in a convenient 100µg size. CSNK1A1 (Casein Kinase 1 Alpha 1), also known as CK1α1, is a member of the CK1 family of serine/threonine protein kinases, known for their pivotal roles in regulating diverse cellular processes, including circadian rhythms, cell cycle progression, and signaling.

This carefully designed antibody is rigorously validated for specificity and sensitivity, making it ideal for applications such as immunohistochemistry, kinase activity assays, and studies into developmental biology and circadian rhythms. Whether you are researching CK1α1's contributions to circadian clock regulation, its interactions with cell cycle regulators, or its potential as a therapeutic target, our Anti-CSNK1A1 Antibody will provide you with accurate and consistent results.

Count on the accuracy and reliability of this antibody as you delve into the intricate roles of CSNK1A1 in health and disease. Uncover the molecular mechanisms governing CK1-mediated signaling and its implications for therapeutic interventions and diagnostics with the assistance of this high-quality antibody.

Product Name

CSNK1A1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis(PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration(PubMed:23902688).

IMMUNOGEN INFORMATION

Immunogen

casein kinase 1, alpha 1

Observed MW

42-45 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P48729

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