anti- CXCR4 antibody

Our Anti-CXCR4 Antibody, available in a convenient 100µg size, is an essential resource for researchers studying CXCR4, a chemokine receptor with critical roles in immune cell migration, hematopoiesis, and cancer metastasis.

CXCR4, also known as C-X-C chemokine receptor type 4, is a key player in various physiological and pathological processes, making it a central focus of research in diverse fields. With our antibody, you can confidently investigate the functions and interactions of CXCR4, gaining insights into its significance in cellular biology.

We have rigorously validated the specificity and sensitivity of this antibody to ensure accurate and reproducible results in your experiments. Its compact size allows for versatility in applications, whether you're conducting flow cytometry, immunohistochemistry, or in vivo studies. Trust in the quality of our Anti-CXCR4 Antibody to advance your scientific investigations and contribute to a deeper understanding of chemokine receptor signaling.

Product Name

CXCR4 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The chemokine receptor CXCR4, a 7-transmembrane protein on cell surface, acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart, white blood cells, vascular endothelial cells, and umbilical cord endothelial cells. Several CXCR4 isoforms have been identified with molecular weights of 47, 50, 62 and 98kDa. The 62-64kDa CXCR4 is predominantly ubiquitinated and is preferentially associated with CD4. This antibody recognizes the 62kd CXCR4.

IMMUNOGEN INFORMATION

Immunogen

chemokine(C-X-C motif) receptor 4

Synonyms

CD184, CXC R4, CXCR 4, CXCR4, CXCR4B, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, LESTR, SDF 1 receptor, WHIM

Observed MW

60-70kd

APPLICATION

Tested Application

ELISA, WB, FC

Recommended Dilution

WB: 1:500-1:5000

UNIPROT INFORMATION

UniProt ID

P61073

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