anti- CYP2C8 antibody

Our Anti-CYP2C8 Antibody, available in a convenient 100µg size, is an essential tool for researchers exploring the cytochrome P450 enzyme CYP2C8, known for its involvement in the metabolism of various drugs, including antidiabetic medications.

Understanding the functions and genetic variations of CYP2C8 is essential for unraveling its contributions to drug metabolism and the potential for drug-drug interactions. Our antibody has been meticulously validated for specificity and sensitivity, ensuring reliable results in your experiments.

Its compact size allows for versatility in applications, whether you're conducting drug metabolism studies, pharmacogenomic research, or investigating the impact of genetic polymorphisms. Trust in the quality of our Anti-CYP2C8 Antibody to accelerate your scientific investigations and contribute to advancements in pharmacology and personalized medicine.

Product Name

CYP2C8 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15-and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel(taxol).

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 2, subfamily C, polypeptide 8

Synonyms

CPC8, CYP2C8, CYPIIC8, Cytochrome P450 2C8

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:500-1:1000

UNIPROT INFORMATION

UniProt ID

P10632

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