anti- CYP4A11 antibody

Our Anti-CYP4A11 Antibody, available in a 100µg size, is an indispensable tool for researchers studying the cytochrome P450 enzyme CYP4A11, known for its role in the metabolism of arachidonic acid and the synthesis of biologically active eicosanoids.

CYP4A11 is involved in the hydroxylation of arachidonic acid, leading to the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), a potent vasoconstrictor and regulator of blood pressure. Understanding the functions and regulation of CYP4A11 is essential for unraveling its contributions to eicosanoid signaling pathways and its implications in cardiovascular physiology and hypertension.

Our antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in your experiments. Its compact size allows for versatility in applications, whether you're conducting eicosanoid metabolism studies, investigating vascular regulation, or exploring therapeutic targets. Trust in the quality of our Anti-CYP4A11 Antibody to accelerate your scientific investigations and contribute to advancements in cardiovascular and hypertension research.

Product Name

CYP4A11 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalyzes the omega-and(omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid(20-HETE).

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 4, subfamily A, polypeptide 11

Synonyms

CYP4A2

Observed MW

59kd

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q02928

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