anti- CYP51A1 antibody

Our Anti-CYP51A1 Antibody, available in a 100µg size, is a crucial tool for researchers studying the cytochrome P450 enzyme CYP51A1, also known as lanosterol 14-alpha demethylase, involved in sterol biosynthesis.

CYP51A1 is responsible for the conversion of lanosterol to cholesterol, making it a pivotal player in cholesterol biosynthesis and essential for the growth and survival of many pathogens. Understanding the functions and regulation of CYP51A1 is essential for unraveling its contributions to sterol metabolism and its implications in fungal infections and drug development.

Our antibody has undergone rigorous validation for specificity and sensitivity, ensuring accurate and reproducible results in your experiments. Its compact size allows for versatility in applications, whether you're conducting sterol biosynthesis studies, investigating antifungal drug mechanisms, or exploring therapeutic targets. Trust in the quality of our Anti-CYP51A1 Antibody to accelerate your scientific investigations and contribute to advancements in microbiology and drug discovery.

Product Name

CYP51A1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 51, subfamily A, polypeptide 1

Synonyms

CYP51

Observed MW

63 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q16850

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