anti- Cytokeratin 19 antibody

Our Anti-Cytokeratin 19 Antibody, available in a 100µg size, is a valuable tool for researchers investigating the expression and distribution of cytokeratin 19, a type I cytokeratin protein found in various epithelial tissues.

Accurate detection and quantification of cytokeratin 19 are crucial for understanding its role in tissue differentiation and its potential as a marker for diagnosing epithelial tumors and carcinomas. This antibody has undergone rigorous validation for specificity and sensitivity, ensuring reliable results in applications such as immunohistochemistry and immunofluorescence.

With its compact size, this antibody offers versatility in experimental approaches, allowing you to explore cytokeratin 19 expression and localization in different tissues and cell types. Trust in the quality of our Anti-Cytokeratin 19 Antibody to advance your research and deepen your understanding of cytokeratin biology and its clinical applications.

Product Name

Cytokeratin 19 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.

IMMUNOGEN INFORMATION

Immunogen

keratin 19

Synonyms

CK 19, CK19, Cytokeratin 19, K19, K1CS, keratin 19, KRT19

Observed MW

44-50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P08727

IMAGES