anti- DHDDS antibody

The anti-DHDDS antibody, available in a 100µg size, is a vital tool for researchers studying the DHDDS (Dehydrodolichyl Diphosphate Synthase) enzyme, which plays a crucial role in the biosynthesis of dolichol, an essential lipid involved in N-glycosylation and protein folding.

This antibody is meticulously designed to specifically target DHDDS with exceptional specificity and sensitivity, making it ideal for applications such as Western blotting, immunohistochemistry, and studies related to lipid metabolism, protein glycosylation, and cellular trafficking.

Our anti-DHDDS antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. Researchers investigating glycosylation pathways, lipid biology, or the role of DHDDS in congenital disorders will find this antibody indispensable for their work.

With a 100µg size, each vial provides ample supply for multiple experiments, allowing for flexibility in experimental design. Whether exploring DHDDS's function in protein glycosylation, congenital disorders, or its implications in neurodegenerative diseases, this antibody is an essential resource for your research.

Product Name

DHDDS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

With DHDDS, forms the dehydrodolichyl diphosphate synthase(DDS) complex, an essential component of the dolichol monophosphate(Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate(IPP) to farnesyl pyrophosphate(FPP) to produce dehydrodolichyl diphosphate(Dedol-PP), a precusrosor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum(ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol.

IMMUNOGEN INFORMATION

Immunogen

dehydrodolichyl diphosphate synthase

Synonyms

HDS

Observed MW

34 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q86SQ9

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