anti- DIS3L antibody

The anti-DIS3L antibody, available in a 100µg size, is a versatile tool for researchers studying the DIS3L (DIS3-like exonuclease 1) protein, a key player in RNA metabolism and surveillance. DIS3L is involved in maintaining RNA quality control and regulating gene expression by targeting specific RNA substrates for degradation.

This antibody is engineered to provide high specificity and sensitivity, making it suitable for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. Researchers can confidently explore DIS3L's functions in RNA degradation pathways, RNA quality control mechanisms, and its relevance to various biological processes.

With 100µg of product in each vial, researchers have an ample supply for multiple experiments, offering flexibility and cost-efficiency in their research designs. The antibody undergoes rigorous quality control procedures to ensure consistent and reproducible results, providing researchers with the confidence to pursue their scientific inquiries effectively.

Product Name

DIS3L antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

IMMUNOGEN INFORMATION

Immunogen

DIS3 mitotic control homolog-like

Synonyms

DIS3L1, KIAA1955

Observed MW

121 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q8TF46

IMAGES