anti- DKC1 antibody

The anti-DKC1 antibody, provided in a 100µg size, is a crucial tool for researchers exploring the intricate roles of DKC1 (Dyskerin Pseudouridine Synthase 1) in RNA modification, telomere maintenance, and its potential implications in cancer and genetic disorders.

This high-quality antibody is optimized for specificity and sensitivity, making it suitable for various applications, including Western blotting, immunoprecipitation, and studies investigating DKC1's functions in ribosome biogenesis and RNA pseudouridylation.

Our anti-DKC1 antibody undergoes rigorous quality control to ensure consistent and reliable performance in experiments. With 100µg of product, you have a sufficient quantity for multiple experiments and the flexibility to tailor your research design.

Product Name

DKC1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

dyskeratosis congenita 1, dyskerin

Synonyms

NOLA4

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O60832

IMAGES