anti- DMAP1 antibody

The anti-DMAP1 antibody, available in a 100µg size, is an essential research tool for scientists investigating DMAP1 (DNA Methyltransferase 1-Associated Protein 1). This antibody offers high specificity and sensitivity, making it suitable for various applications, including Western blotting and immunohistochemistry.

DMAP1 is known to play a crucial role in epigenetic regulation by interacting with DNA methyltransferases and histone deacetylases. Researchers can utilize this antibody to explore the functions of DMAP1 in chromatin remodeling, gene expression regulation, and its potential roles in cancer and development.

Rigorous quality control ensures the reliability and consistency of results, providing researchers with the confidence to pursue their scientific inquiries effectively. With 100µg of product per vial, it offers a sufficient quantity for multiple experiments, ensuring cost-effectiveness and experimental flexibility.

In summary, the anti-DMAP1 antibody is a high-quality reagent that empowers researchers to investigate the roles of DMAP1 in epigenetic regulation and its implications in various biological processes. By studying DMAP1, researchers can contribute to our understanding of chromatin dynamics and epigenetic mechanisms.

Product Name

DMAP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

IMMUNOGEN INFORMATION

Immunogen

DNA methyltransferase 1 associated protein 1

Synonyms

KIAA1425

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:1000 - 1:4000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9NPF5

IMAGES