anti- DNAJA1 antibody

The anti-DNAJA1 antibody, available in a 100µg size, is a crucial research tool for scientists studying DNAJA1 (DnaJ Heat Shock Protein Family Member A1), a chaperone protein involved in protein folding and cellular stress response. This antibody offers high specificity and sensitivity, making it suitable for various applications, including immunohistochemistry and Western blotting.

DNAJA1 plays a pivotal role in facilitating proper protein folding and protecting cells from stress-induced damage. Researchers can employ this antibody to explore the expression patterns and functions of DNAJA1, shedding light on its intricate roles in maintaining cellular homeostasis.

Rigorous quality control ensures the reliability and consistency of results, providing researchers with the confidence to advance their scientific investigations effectively. With 100µg of product per vial, it offers an ample supply for multiple experiments, ensuring cost-effectiveness and experimental flexibility.

In summary, the anti-DNAJA1 antibody is a high-quality reagent that empowers researchers to investigate the roles of DNAJA1 in protein folding and stress response. By studying DNAJA1, researchers can contribute to our understanding of fundamental cellular processes and their implications in health and disease.

Product Name

DNAJA1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Co-chaperone for HSPA8/Hsc70(PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A(in vitro)(PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis(PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV(PubMed:24512202).

IMMUNOGEN INFORMATION

Immunogen

DnaJ(Hsp40) homolog, subfamily A, member 1

Synonyms

DJ 2, DjA1, DnaJ protein homolog 2, DNAJ2, DNAJA1, hDJ 2, HDJ2, Heat shock 40 kDa protein 4, Heat shock protein J2, HSDJ, HSJ 2, HSJ2, HSPF4, Human DnaJ protein 2

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P31689

IMAGES