anti- DYNLT1 antibody

Embark on a journey into the intricate world of intracellular transport with our meticulously designed Anti-DYNLT1 Antibody, now available in a 100µg size. DYNLT1, also known as Tctex1, is a vital component of the dynein motor complex, essential for retrograde transport along microtubules. This antibody is a powerful tool for researchers investigating motor protein interactions, organelle dynamics, and cellular processes.

This highly specific antibody empowers you to investigate the nuances of DYNLT1 and its functions with precision and confidence. It has undergone rigorous quality control to ensure accuracy and reproducibility in your experiments, making it an ideal choice for researchers studying intracellular transport, vesicle trafficking, and their implications in health and disease.

DYNLT1 plays a central role in cargo transport within cells and is critical for proper cellular function. Whether your research focuses on intracellular dynamics, neurodegenerative diseases, or cell division, this antibody is your invaluable research companion.

Order your 100µg vial today and unlock the secrets of DYNLT1, its role in intracellular transport, and its significance in various cellular processes.

Product Name

DYNLT1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation(By similarity).

IMMUNOGEN INFORMATION

Immunogen

dynein, light chain, Tctex-type 1

Synonyms

TCTEL1, TCTEX-1, TCTEX1

Observed MW

12 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P63172

IMAGES