anti- EBI3 antibody

Venture into the realm of immunoregulation with our Anti-EBI3 Antibody, now available in a 100µg size. EBI3, also known as Epstein-Barr Virus-Induced Gene 3, is a pivotal cytokine subunit involved in immune response modulation and inflammation control.

This antibody is extensively validated for specificity, making it an indispensable tool for researchers investigating immunoregulation, cytokine signaling, and autoimmune diseases.

EBI3's significance in immunoregulation and its role in immune response modulation have made it a subject of substantial research interest in the fields of immunology and autoimmune disease. Whether your research focuses on cytokine networks, immune disorders, or inflammatory diseases, this antibody is an invaluable addition to your toolkit.

Product Name

EBI3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro-and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells(TH1), type 2 effector cells(TH2) and IL17 producing helper T-cells(TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.

IMMUNOGEN INFORMATION

Immunogen

Epstein-Barr virus induced 3

Synonyms

IL27B

Observed MW

25-35 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q14213

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