anti- EED antibody

Dive into the intricate world of chromatin regulation with our Anti-EED Antibody, now available in a 100µg size. EED, also known as Embryonic Ectoderm Development, is a core component of the Polycomb Repressive Complex 2 (PRC2).

This antibody is extensively validated for specificity, making it an essential tool for researchers investigating epigenetic control, gene expression, and chromatin structure.

EED's significance in chromatin regulation and its role in maintaining gene silencing have made it a subject of substantial research interest in the fields of molecular biology and epigenetics. Whether your research focuses on gene silencing, epigenetic modifications, or chromatin structure, this antibody is an invaluable addition to your toolkit.

Order your 100µg vial today and embark on an exploration of EED, its role in chromatin regulation, and its implications in various biological processes.

Product Name

EED antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Polycomb group(PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

IMMUNOGEN INFORMATION

Immunogen

embryonic ectoderm development

Observed MW

53 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

O75530

IMAGES