anti- EHD1 antibody

Investigate the versatile functions of EHD1 (Eps15 homology domain-containing protein 1) with our Anti-EHD1 Antibody, now available in a 100µg size. EHD1 plays a crucial role in endocytic trafficking, vesicle transport, and membrane remodeling.

This antibody is meticulously validated for specificity, ensuring that your research on EHD1's roles in endocytosis regulation, its interactions with other vesicle-associated proteins, and its implications in cellular processes is backed by a reliable tool.

EHD1's significance in orchestrating vesicle transport and its potential relevance in various cellular events have made it a subject of significant research interest. Whether your research focuses on endocytic pathways, vesicle dynamics, or membrane remodeling mechanisms, this antibody is an indispensable addition to your toolkit.

Order your 100µg vial today and delve into the world of EHD1 to advance your understanding of its functions in cellular processes.

Product Name

EHD1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ATP-and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes vesiculation of endocytic membranes(PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes(PubMed:15020713, PubMed:17233914, PubMed:20801876). Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth(By similarity). Plays a role in myoblast fusion(By similarity). Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing(By similarity). Plays a role in the formation of the ciliary vesicle(CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles(DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis(PubMed:25686250).

IMMUNOGEN INFORMATION

Immunogen

EH-domain containing 1

Synonyms

PAST,

Observed MW

61 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9H4M9

IMAGES