anti- EIF2S1 antibody

Dive into the intricate world of translation initiation with our Anti-EIF2S1 Antibody, now available in a 100µg size. EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1) is a pivotal player in the eukaryotic translation initiation complex, orchestrating the essential process of protein synthesis.

This antibody is meticulously validated for specificity, ensuring that your research on EIF2S1's role in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is bolstered by a reliable tool.

EIF2S1's significance in controlling gene expression and protein synthesis has made it a subject of significant research interest. Whether your studies focus on translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your scientific toolkit.

Order your 100µg vial today and embark on a journey to uncover EIF2S1's functions in the intricate world of cellular processes.

Product Name

EIF2S1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Synonyms

EIF2A

Observed MW

36 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, FC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P05198

IMAGES