anti- EIF3B antibody

Advance your scientific studies with our Anti-EIF3B Antibody, now available in a 100µg size. EIF3B (Eukaryotic Translation Initiation Factor 3 Subunit B) is an integral part of the eukaryotic translation initiation complex.

This antibody is extensively validated for specificity, ensuring that your research on EIF3B's role in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is supported by a reliable tool.

EIF3B's significance in controlling gene expression and protein synthesis has made it a subject of substantial research interest. Whether your research focuses on translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your scientific toolkit.

Order your 100µg vial today and accelerate your investigations into EIF3B and its contributions to cellular processes.

Product Name

EIF3B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit B

Synonyms

eIF 3 eta, EIF3 ETA, EIF3 P110, EIF3 P116, EIF3B, EIF3S9, hPrt1, PRT1, Prt1 homolog

Observed MW

120 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

P55884

IMAGES