anti- EIF3L antibody

Decipher the intricacies of gene regulation with our Anti-EIF3L Antibody, now available in a 100µg size. EIF3L (Eukaryotic Translation Initiation Factor 3 Subunit L) is a crucial component of the eukaryotic translation initiation factor 3 complex, playing a central role in controlling protein synthesis and gene expression.

This antibody is meticulously validated for specificity, ensuring that your research on EIF3L's role in translation initiation, its interactions with other translation factors, and its implications in various cellular processes is fortified by a reliable tool.

EIF3L's significance in orchestrating gene expression and regulating protein synthesis has made it a subject of substantial research interest. Whether your studies focus on translation initiation, ribosome assembly, or gene regulation, this antibody is an indispensable addition to your research toolkit.

Order your 100µg vial today and advance your studies into EIF3L and its contributions to gene regulation and protein synthesis.

Product Name

EIF3L antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 3, subunit L

Synonyms

EIF3EIP,

Observed MW

67 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9Y262

IMAGES