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FineTest

SKU(재고 관리 코드):FNab02717

anti- EIF4A2 antibody

anti- EIF4A2 antibody

size

Embark on a journey of RNA exploration with our Anti-EIF4A2 Antibody, available in a 100µg size. EIF4A2 (Eukaryotic Translation Initiation Factor 4A2) is an RNA helicase that plays a crucial role in the initiation of translation by unwinding mRNA secondary structures, facilitating ribosome binding, and enhancing protein synthesis.

This antibody is rigorously validated for specificity, ensuring that your research into EIF4A2's RNA unwinding activity, its implications in translational control, and its role in RNA metabolism is empowered by a reliable tool. Whether your studies focus on the intricacies of RNA helicases, translation initiation, or mRNA processing, this antibody is an invaluable addition to your scientific toolkit.

Order your 100µg vial today and delve into the realm of EIF4A2, unraveling its significance in RNA-related processes.

Product Name

EIF4A2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

IMMUNOGEN INFORMATION

Immunogen

eukaryotic translation initiation factor 4A, isoform 2

Synonyms

BM 010, DDX2B, eIF 4A II, EIF4A, eIF4A II, EIF4A2, EIF4F

Observed MW

47kd

APPLICATION

Tested Application

ELISA, WB, IF, IHC, IP

Recommended Dilution

WB: 1:200-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q14240

IMAGES

 

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab02717(EIF4A2 antibody) at dilution of 1:100
IP Result of anti-EIF4A2 (IP:FNab02717, 4ug; Detection:FNab02717 1:500) with Jurkat cells lysate 4000ug.
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab02717(EIF4A2 antibody) at dilution of 1:400

 

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