anti- ELAC2 antibody

Investigate ELAC2 (ElaC Ribonuclease Z 2) with our Anti-ELAC2 Antibody, now available in a 100µg size. ELAC2 is an endoribonuclease that plays a pivotal role in tRNA maturation and RNA processing, contributing to the fidelity of protein synthesis.

This antibody is meticulously validated for specificity, ensuring its suitability for research into ELAC2's function, its role in RNA processing pathways, and its implications in cellular processes. Whether your studies focus on tRNA biology, RNA metabolism, or translational control, this antibody is an invaluable tool for your research.

Enhance your understanding of ELAC2 and its contributions to RNA processing by ordering your 100µg vial today. With this antibody, you can advance your research into the intricate world of RNA biology and protein synthesis.

Product Name

ELAC2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

elaC homolog 2 (E. coli)

Synonyms

HPC2

Observed MW

105 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q9BQ52

IMAGES