anti- EPHB4 antibody

Delve into the intricate world of cellular signaling and vascular biology with our Anti-EPHB4 Antibody, an essential tool for studying EPHB4, a prominent member of the Eph receptor family. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

EPHB4 is a critical player in regulating blood vessel formation and tissue development, influencing various physiological processes. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for applications like immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-EPHB4 Antibody is your key to unraveling the functions of EPHB4, contributing to a deeper understanding of vascular biology. Whether you're engaged in basic research or vascular disease studies, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

EPHB4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

IMMUNOGEN INFORMATION

Immunogen

EPH receptor B4

Synonyms

EPH receptor B4, EPHB4, Ephrin type B receptor 4, HTK, MYK1, TYRO11, Tyrosine protein kinase TYRO11

Observed MW

110kd

APPLICATION

Tested Application

ELISA, IHC, FC, WB

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P54760

IMAGES