anti- EPOR antibody

Uncover the intricacies of erythropoietin signaling with our Anti-EPOR Antibody, a high-quality 100µg polyclonal antibody. EPOR (Erythropoietin Receptor) is a pivotal player in the regulation of red blood cell production, impacting various physiological processes and tissue oxygenation.

This polyclonal antibody has been rigorously tested for specificity and sensitivity, making it suitable for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. Whether you're conducting fundamental research or exploring therapeutic possibilities, this antibody offers the precision and reliability needed for successful experiments and meaningful discoveries.

The Anti-EPOR Polyclonal Antibody is your key to understanding the functions of EPOR and its role in erythropoietin signaling.

Product Name

EPOR antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

erythropoietin receptor

Synonyms

EPO R, EPOR, erythropoietin receptor

Observed MW

53 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P19235

IMAGES