anti- ERBB4 antibody

Embark on a journey into the world of cell signaling and oncology with our Anti-ERBB4 Antibody, a crucial tool for studying ERBB4, a prominent member of the ERBB receptor family. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERBB4 is a key player in mediating cell signaling, impacting various physiological processes, including cell proliferation and cancer progression. Our antibody is meticulously tested for specificity and sensitivity, making it suitable for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERBB4 Antibody is your key to understanding the functions of ERBB4 and its contributions to cell biology and oncology. Whether you're engaged in basic research or cancer therapy development, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERBB4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

IMMUNOGEN INFORMATION

Immunogen

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Synonyms

HER4

Observed MW

180 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

Q15303

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