anti- ESR2 antibody

Delve into the world of estrogen receptor beta (ESR2) with our Anti-ESR2 Antibody, a crucial tool for your scientific explorations. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ESR2 is a nuclear receptor with significant implications in hormone signaling, cellular physiology, and reproductive biology. It plays a central role in mediating estrogen effects. Our antibody is rigorously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunohistochemistry.

The Anti-ESR2 Antibody is your indispensable resource for understanding the functions of ESR2 and its contributions to hormone-related processes and diseases. Whether you're engaged in basic research or investigating hormone-related conditions, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ESR2 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements(ERE) in an estrogen-dependent manner(PubMed:20074560). Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

IMMUNOGEN INFORMATION

Immunogen

estrogen receptor 2(ER beta)

Synonyms

ER BETA, Erb, ESR BETA, ESR2, ESRB, ESTRB, estrogen receptor 2 (ER beta), Estrogen receptor beta, NR3A2

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q92731

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