anti- FADD antibody

Enter the world of cell signaling and apoptosis research with our Anti-FADD Antibody, an essential tool for studying Fas-Associated Death Domain (FADD) protein, a key player in programmed cell death pathways. FADD is pivotal in transmitting death signals from cell surface receptors to the intracellular apoptotic machinery, making it a fundamental target for understanding cell fate decisions. This high-quality antibody, available in a 100µg size, is your trusted partner for unraveling the intricacies of cell death signaling.

The Anti-FADD Antibody has been meticulously developed and rigorously validated to ensure exceptional specificity and sensitivity. It empowers you to explore FADD's multifaceted functions, from its role in apoptosis regulation to its implications in cancer, autoimmune diseases, and immunodeficiencies, with confidence in the reliability of your results.

With 100µg at your disposal, this antibody minimizes the need for frequent reordering, ensuring a seamless and uninterrupted research experience. Whether you're studying cell signaling pathways, investigating the role of FADD in programmed cell death, or exploring its implications in various diseases, this antibody adapts effortlessly to a wide range of research applications.

Product Name

FADD antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.

IMMUNOGEN INFORMATION

Immunogen

Fas(TNFRSF6)-associated via death domain

Synonyms

FADD, GIG3, MORT1, Protein FADD

Observed MW

26 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IP

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q13158

IMAGES