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FineTest

SKU(재고 관리 코드):FNab02979

anti- FAM20C antibody

anti- FAM20C antibody

size

Explore the intricate world of cellular regulation and molecular interactions with our Anti-FAM20C Antibody, a vital tool for studying Family with Sequence Similarity 20 Member C (FAM20C). FAM20C plays a critical role in various cellular functions, making it a central focus for understanding cell biology and molecular interactions. This high-quality antibody, available in a 100µg size, empowers you to delve into the intricacies of FAM20C's roles.

The Anti-FAM20C Antibody has undergone meticulous development and rigorous validation to ensure exceptional specificity and sensitivity. It enables you to explore FAM20C's multifaceted functions, from its involvement in cellular signaling to its implications in disease, immunology, and developmental biology, with confidence in the reliability of your results.

With 100µg at your disposal, this antibody minimizes the need for frequent reordering, ensuring a seamless and uninterrupted research experience. Whether you're studying cell signaling pathways, investigating the role of FAM20C in disease mechanisms, or exploring its implications in immune responses, this antibody adapts seamlessly to a wide range of research applications.

Product Name

FAM20C antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039).

IMMUNOGEN INFORMATION

Immunogen

family with sequence similarity 20, member C

Synonyms

Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS

Observed MW

50 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q8IXL6

IMAGES

 

Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab02979(FAM20C Antibody) at dilution of 1:50
various lysates were subjected to SDS PAGE followed by western blot with FNab02979(FAM20C Antibody) at dilution of 1:600

 

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