anti- FBP1 antibody

Explore the intricate world of Fructose-1,6-Bisphosphatase 1 (FBP1) with our Anti-FBP1 Antibody, a powerful tool designed for researchers in cellular and molecular biology. FBP1 plays a pivotal role in gluconeogenesis, making it a significant target for studies related to metabolism and diabetes. Our high-quality antibody, available in a 100µg size, provides you with the precision and sensitivity needed to delve into the functions and regulatory mechanisms of FBP1.

This Anti-FBP1 Antibody has been meticulously developed and rigorously validated to ensure its specificity and reliability. It enables you to study FBP1's involvement in glucose metabolism, its response to hormonal signaling, and its potential implications in various metabolic disorders.

With 100µg of this antibody at your disposal, you can minimize the need for frequent reordering, ensuring a smooth and uninterrupted research experience. Whether you are investigating FBP1's role in glucose homeostasis, its association with cancer, or its potential therapeutic applications, this antibody adapts seamlessly to a wide range of research applications.

Product Name

FBP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

IMMUNOGEN INFORMATION

Immunogen

fructose-1,6-bisphosphatase 1

Synonyms

FBP, FBP1, FBPase 1, fructose 1,6 bisphosphatase 1

Observed MW

37 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF, IP

Recommended Dilution

WB: 1:5000-1:20000; IP: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P09467

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