anti- FBXO2 antibody

Delve into the intricate world of cellular regulation and discover the essential role of the FBXO2 protein with our meticulously validated Anti-FBXO2 Antibody, available in a generous 100µg size. FBXO2, a critical component of the ubiquitin-proteasome system, governs the targeted degradation of specific proteins, influencing a myriad of cellular processes. This antibody is your trusted ally in unraveling the complexities of cellular dynamics.

Key Features:

1. Ample 100µg Quantity: With 100µg of our Anti-FBXO2 Antibody, you have a substantial amount of material to conduct a wide range of experiments, ensuring your research remains cost-effective and dependable.

2. Rigorous Validation: Our Anti-FBXO2 Antibody has undergone meticulous validation to guarantee specificity and reliability. This minimizes the risk of non-specific interactions and ensures that your results are accurate.

3. Explore Cellular Dynamics: Investigate the role of FBXO2 in regulating protein degradation, cellular dynamics, and its broader implications in cell biology. Your research has the potential to uncover groundbreaking insights into disease mechanisms and therapeutic targets.

4. Potential Therapeutic Clues: By examining the potential connections between FBXO2 and various diseases, your research may pave the way for novel therapeutic avenues and a deeper understanding of disease development.

5. Contribute to Scientific Advancements: Join a community of leading researchers who rely on our Anti-FBXO2 Antibody to advance their understanding of regulatory proteins and their role in maintaining healthy cellular function.

Whether you are exploring FBXO2's role in protein degradation or investigating its broader connections to diseases, our antibody empowers you to conduct accurate and reliable research, shedding light on the intricacies of cellular regulation.

Product Name

FBXO2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway(ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type(By similarity).

IMMUNOGEN INFORMATION

Immunogen

F-box protein 2

Synonyms

FBX2

Observed MW

33-40 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UK22

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