anti- FER antibody

Introducing our Anti-FER Antibody, a vital tool for researchers delving into the intricate world of cellular signaling and molecular mechanisms. This antibody is available in a generous 100µg size, providing you with an ample supply to fuel your scientific inquiries.

Key Features:

1. 100µg of High-Quality Antibody: With 100µg of our meticulously validated Anti-FER Antibody at your disposal, you'll have more than enough reagent for your research, ensuring that you can carry out a wide range of experiments.

2. Targeting the FER Gene: FER, also known as Fer Tyrosine Kinase, is a multifunctional protein involved in various cellular processes, making it a compelling target for research. By using our antibody, you'll gain insights into its role in signal transduction and its impact on cell behavior.

3. Stringent Validation: Our antibody has undergone rigorous validation to ensure specificity, accuracy, and reliability in your experiments. You can trust your results to be accurate and consistent.

4. Diverse Research Applications: Unlock the potential of FER research across multiple domains, including cell signaling, kinase activity, and its association with cancer and other diseases. This versatile antibody can contribute to a wide array of research projects.

5. Aiding Therapeutic Development: By elucidating the roles of FER, your research may offer valuable contributions to the development of therapeutic strategies targeting diseases related to cellular signaling and kinase function.

6. Supportive Scientific Community: Join a community of fellow researchers who have successfully harnessed the power of our Anti-FER Antibody to drive their scientific inquiries forward.

Product Name

FER antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide(LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.

IMMUNOGEN INFORMATION

Immunogen

fer(fps/fes related) tyrosine kinase

Synonyms

TYK3

Observed MW

95 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, FC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P16591

IMAGES