anti- FHIT antibody

Delve into the fascinating world of Fragile Histidine Triad Protein (FHIT) with our Anti-FHIT Antibody, a polyclonal antibody available in a 100µg vial. FHIT is a tumor suppressor protein known for its involvement in DNA damage repair and cell growth regulation. This highly specific polyclonal antibody empowers researchers to explore the multifaceted role of FHIT in cancer biology, cellular integrity, and beyond with precision and reliability.

Key Features:

• Polyclonal Versatility: This antibody offers the advantages of polyclonal antibodies, allowing for multiple applications, including Western blotting, immunohistochemistry, and immunoprecipitation.
• Exceptional Specificity: Our Anti-FHIT Antibody is rigorously tested for its specificity, ensuring accurate and reliable results while minimizing cross-reactivity.
• Ample Quantity: The 100µg size guarantees you have an abundant supply for multiple experiments, optimizing cost-effectiveness.
• Top-Tier Quality: Manufactured to industry-leading standards, this antibody assures consistent and reproducible results.
• Advance Your Research: Whether your focus is on cancer biology, DNA damage repair, or cell growth regulation, our Anti-FHIT Antibody empowers your research with polyclonal precision.

Unveil the secrets of FHIT with our Anti-FHIT Polyclonal Antibody.

Product Name

FHIT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene, a member of the histidine triad gene family, encodes a diadenosine 5', 5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

FHIT

Synonyms

AP3Aase, FRA3B

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P49789

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