anti- FLNB antibody

Uncover the role of Filamin-B (FLNB) in cellular processes with our Anti-FLNB Antibody, available in a 100µg vial. FLNB is a fundamental protein that shapes the cytoskeleton and regulates cell motility. This highly specific antibody empowers researchers to investigate FLNB and its functions in detail, contributing to a deeper understanding of its influence on various cellular functions.

Key Features:

• Exceptional Specificity: Our Anti-FLNB Antibody is rigorously tested to ensure it accurately targets Filamin-B, minimizing the risk of cross-reactivity.
• Versatile Applications: Ideal for a wide range of experimental techniques, including immunohistochemistry, Western blotting, and immunofluorescence.
• Ample Quantity: With 100µg, you have a generous supply for multiple experiments.
• Top-Tier Quality: Manufactured to the highest industry standards, guaranteeing consistent and reproducible results.
• Advance Your Research: Whether you're exploring cytoskeletal dynamics, cell motility, or other cellular functions, our Anti-FLNB Antibody is your key to uncovering the role of FLNB.

Product Name

FLNB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

IMMUNOGEN INFORMATION

Immunogen

filamin B, beta (actin binding protein 278)

Synonyms

FLN1L, FLN3, TABP, TAP

Observed MW

298 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:1000; IHC: 1:20 - 1:50

UNIPROT INFORMATION

UniProt ID

O75369

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