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FNab03184

anti- FOLR1 antibody

anti- FOLR1 antibody

size

Investigate Folate Receptor 1 (FOLR1) in research and diagnosis with our Polyclonal Anti-FOLR1 Antibody, available in a 100µg vial. FOLR1 is a cell surface receptor involved in folate uptake and is associated with various diseases. This highly specific polyclonal antibody empowers researchers to explore FOLR1 and its functions, whether you're studying folate metabolism, cancer, or other fields.

Key Features:

  • Exceptional Specificity: Our Polyclonal Anti-FOLR1 Antibody is rigorously tested to ensure it accurately targets FOLR1, minimizing the risk of cross-reactivity.
  • Polyclonal Advantage: Polyclonal antibodies offer enhanced sensitivity, ideal for detecting low-abundance targets.
  • Versatile Applications: Suitable for various experimental techniques, including immunohistochemistry, Western blotting, and flow cytometry.
  • Ample Quantity: With 100µg, you have a generous supply for multiple experiments.
  • Top-Tier Quality: Manufactured to the highest industry standards, guaranteeing consistent and reproducible results.

Product Name

FOLR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

IMMUNOGEN INFORMATION

Immunogen

folate receptor 1

Synonyms

Adult folate binding protein, FBP, Folate receptor 1, folate receptor 1(adult), Folate receptor alpha, Folate receptor, adult, FOLR, FOLR1, FR alpha

Observed MW

38 kDa

APPLICATION

Tested Application

ELISA, WB, IF,IHC

Recommended Dilution

WB: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P15328

IMAGES

 

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab03184(FOLR1 Antibody) at dilution of 1:100
Immunofluorescent analysis of HeLa cells using FNab03184 (FOLR1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03184(FOLR1 Antibody) at dilution of 1:1000

 

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